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PTCB Pharmacy Technician Certification Exam

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Questions updated at Aug 23, 2026, 8:12 PM CDT

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Today's 10 PTCE questions

Use this PTCE practice test to review PTCB Pharmacy Technician Certification Exam. Questions rotate daily and each answer links back to the source used to write it.

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200 verified questions are in the live bank. Free daily questions are selected from a rotating sample set. Unlock Pro to access the full question bank.

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Question 1 of 10
Objective 2.1 Storage, handling, and disposal of pharmaceutical wastes 2. Federal Requirements

To clear an open container quickly, staff plan to pour a noncontrolled pharmaceutical into the sink without first determining its waste stream. The product may be hazardous under Subpart P. What should occur?

Concept tested:
Question 2 of 10
Objective 1.7 Drug stability 1. Medications

After reconstituting amoxicillin suspension for a pediatric prescription, a technician copies the concentration, storage directions, and discard date from a different manufacturer's product with the same drug name. What should be done?

Concept tested:
Question 3 of 10
Objective 4.1 Formulas, calculations, conversions, Sig codes, and days supply 4. Order Entry and Processing

A prescription directs the patient to take one-half tablet twice daily. The pharmacy dispenses 60 tablets. What days supply should the technician enter?

Concept tested:
Question 4 of 10
Objective 2.2 Controlled substance prescriptions, transfers, refills, and schedules 2. Federal Requirements

A Schedule II prescription was only partially dispensed because the pharmacy lacked the full quantity. The patient returns for the remainder. What should the technician do?

Concept tested:
Question 5 of 10
Objective 3.4 Adverse-event reporting, near misses, root-cause analysis, and CQI 3. Patient Safety and Quality Assurance

A patient reports a potentially serious adverse event at the counter. A technician wants to finish a MedWatch form before notifying anyone or addressing the patient. What is the correct sequence?

Concept tested:
Question 6 of 10
Objective 1.2 Therapeutic duplications 1. Medications

A patient with active warfarin therapy presents a new apixaban prescription, but neither the profile nor the order explains whether this is a transition or an intended combination. What should happen?

Concept tested:
Question 7 of 10
Objective 4.3 Lot numbers, expiration dates, and National Drug Code numbers 4. Order Entry and Processing

A lot-specific recall notice identifies one product and manufacturing lot. Staff shortcut the match by quarantining every package with the same expiration date. Which inventory should actually be quarantined?

Concept tested:
Question 8 of 10
Objective 2.3 Receiving, storing, ordering, labeling, dispensing, return, loss, and destruction of controlled substances 2. Federal Requirements

To speed a Schedule II stock order, staff use the routine Schedule III–V process and share one CSOS credential on a posted note. Which correction is required?

Concept tested:
Question 9 of 10
Objective 3.2 Error-prevention strategies 3. Patient Safety and Quality Assurance

A technician calculates a high-risk dose, tells a coworker the expected result, and asks for an independent check. After an interruption, the coworker signs the worksheet without recalculating. What should happen next?

Concept tested:
Question 10 of 10
Objective 1.6 Indications of medications 1. Medications

A patient says fluticasone HFA is used only when attacks occur and has stopped taking it as scheduled because no symptoms are present today. What correction is appropriate?

Concept tested:
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Question 1 To clear an open container quickly, staff plan to pour a noncontrolled pharmaceutical into the sink without first determining its waste stream. The product may be hazardous under Subpart P. What should occur?

Answer choices

  1. A. Sewer it because only controlled drugs can qualify as hazardous pharmaceutical waste
  2. B. Determine the waste stream; use the hazardous process and do not sewer covered product
  3. C. Place it in ordinary trash because opening the container removes waste controls
  4. D. Return it to dispensable stock because hazardous pharmaceuticals cannot be discarded

Correct answer

Determine the waste stream; use the hazardous process and do not sewer covered product

A noncontrolled drug can still be hazardous pharmaceutical waste, and waste classification must precede disposal. An open container does not authorize sink or ordinary-trash disposal; hazardous waste pharmaceuticals covered by Subpart P may not be sewered.

Wrong-answer review

  • A. Sewer it because only controlled drugs can qualify as hazardous pharmaceutical waste: Federal controlled-substance status and hazardous-waste status are separate regulatory classifications.
  • C. Place it in ordinary trash because opening the container removes waste controls: Opening a container does not erase its hazardous-pharmaceutical waste requirements.
  • D. Return it to dispensable stock because hazardous pharmaceuticals cannot be discarded: Hazardous waste requires a managed disposal stream rather than return to active stock.

Extra learning features

Why candidates miss this

The temptation to simply sewer the product stems from a misunderstanding of the regulatory framework, overlooking the need for a comprehensive waste stream assessment and proper disposal methods. The decisive clue is the requirement for a managed disposal stream rather than return to active stock. Likely wrong answer: Sewer it because only controlled drugs can qualify as hazardous pharmaceutical waste Review focus: Management of Hazardous Waste Pharmaceuticals

Interview question

Q: A noncontrolled drug can still be hazardous pharmaceutical waste, and waste classification must precede disposal. An open container does not authorize sink or ordinary-trash disposal; hazardous waste pharmaceuticals covered by Subpart P may not be sewered. Opening a container does not erase its hazardous-pharmaceutical waste requirements. Strong answer: The waste stream is determined before disposal. Ordinary trash or sink disposal is not selected merely because a container is open. Hazardous waste pharmaceuticals covered by Subpart P may not be sewered.

  • waste stream determination
  • hazardous waste classification
  • Subpart P sewering prohibition
  • open container implications

Caution: This question tests understanding of hazardous waste regulations and disposal procedures.

Why this matters

Failure to properly classify and dispose of hazardous pharmaceutical waste can lead to environmental contamination, posing significant risks to public health and ecosystems, necessitating immediate corrective action. This is a critical consequence of non-compliance.

Objective/domain: 2. Federal Requirements

Source: Management of Hazardous Waste Pharmaceuticals

Question 2 After reconstituting amoxicillin suspension for a pediatric prescription, a technician copies the concentration, storage directions, and discard date from a different manufacturer's product with the same drug name. What should be done?

Answer choices

  1. A. Keep both entries because all amoxicillin suspensions have one universal concentration and date
  2. B. Estimate the final strength from the bottle size and use the pharmacy's longest routine date
  3. C. List only milligrams and omit the volume because suspension concentration does not use mL
  4. D. Reconstitute to labeled strength and follow product-specific storage and discard dating

Correct answer

Reconstitute to labeled strength and follow product-specific storage and discard dating

Objective/domain: 1. Medications

Source: Amoxicillin for Oral Suspension — Official Label

Question 3 A prescription directs the patient to take one-half tablet twice daily. The pharmacy dispenses 60 tablets. What days supply should the technician enter?

Answer choices

  1. A. 15 days
  2. B. 30 days
  3. C. 45 days
  4. D. 60 days

Correct answer

60 days

Objective/domain: 4. Order Entry and Processing

Source: 2026 PTCB Certified Pharmacy Technician Knowledge Reference

Question 4 A Schedule II prescription was only partially dispensed because the pharmacy lacked the full quantity. The patient returns for the remainder. What should the technician do?

Answer choices

  1. A. Treat the remainder as a refill because the original prescription was already used once; involve the pharmacist before completing that step
  2. B. Convert the remaining quantity to Schedule IV so it can be dispensed
  3. C. Dispense the remainder without checking how the original partial fill was documented
  4. D. Refer the order to the pharmacist to verify whether the remaining quantity can be dispensed under the lawful partial-fill process

Correct answer

Refer the order to the pharmacist to verify whether the remaining quantity can be dispensed under the lawful partial-fill process

Question 5 A patient reports a potentially serious adverse event at the counter. A technician wants to finish a MedWatch form before notifying anyone or addressing the patient. What is the correct sequence?

Answer choices

  1. A. Prioritize immediate patient care and pharmacist intervention, then document facts; follow internal and MedWatch reporting procedures
  2. B. Complete external paperwork first because a report replaces immediate clinical response; involve the pharmacist before completing that step
  3. C. Diagnose the medication as the definite cause before documenting the event
  4. D. Submit MedWatch only and omit the pharmacy's internal incident process

Correct answer

Prioritize immediate patient care and pharmacist intervention, then document facts; follow internal and MedWatch reporting procedures

Objective/domain: 3. Patient Safety and Quality Assurance

Source: MedWatch: Reporting Serious Problems to FDA

Question 6 A patient with active warfarin therapy presents a new apixaban prescription, but neither the profile nor the order explains whether this is a transition or an intended combination. What should happen?

Answer choices

  1. A. Dispense both automatically because anticoagulants cannot duplicate one another; involve the pharmacist before completing that step
  2. B. Cancel warfarin independently because every new anticoagulant automatically replaces prior therapy
  3. C. Hold automatic dispensing and have the pharmacist evaluate the transition or combination before both anticoagulants overlap
  4. D. Reclassify apixaban as an antiplatelet so the duplication alert no longer appears

Correct answer

Hold automatic dispensing and have the pharmacist evaluate the transition or combination before both anticoagulants overlap

Objective/domain: 1. Medications

Source: Eliquis (Apixaban) — Official Label

Question 7 A lot-specific recall notice identifies one product and manufacturing lot. Staff shortcut the match by quarantining every package with the same expiration date. Which inventory should actually be quarantined?

Answer choices

  1. A. Every package sharing the expiration date, regardless of product or lot
  2. B. Only inventory matching the recalled product and lot identified in the notice
  3. C. Only inventory with a different lot because unaffected batches require investigation
  4. D. No inventory because an expiration date always replaces lot information

Correct answer

Only inventory matching the recalled product and lot identified in the notice

Objective/domain: 4. Order Entry and Processing

Source: Recalls: Background and Definitions

Question 8 To speed a Schedule II stock order, staff use the routine Schedule III–V process and share one CSOS credential on a posted note. Which correction is required?

Answer choices

  1. A. Keep the routine process because Form 222 and CSOS apply only to Schedule V
  2. B. Use paper Form 222 because CSOS can never be used electronically
  3. C. Share the CSOS certificate because secure credentials work only when everyone can access them
  4. D. Order Schedule II stock with DEA Form 222 or CSOS and protect the CSOS certificate from unauthorized use

Correct answer

Order Schedule II stock with DEA Form 222 or CSOS and protect the CSOS certificate from unauthorized use

Objective/domain: 2. Federal Requirements

Source: Controlled Substance Ordering System Q&A

Question 9 A technician calculates a high-risk dose, tells a coworker the expected result, and asks for an independent check. After an interruption, the coworker signs the worksheet without recalculating. What should happen next?

Answer choices

  1. A. Accept the signature because two employees participated in the workflow
  2. B. Ask the first technician to repeat the result until the coworker agrees
  3. C. Repeat the check independently from the source data before the dose advances
  4. D. Skip the calculation because standardized workflows are optional after an interruption

Correct answer

Repeat the check independently from the source data before the dose advances

Objective/domain: 3. Patient Safety and Quality Assurance

Source: Medication Errors Related to CDER-Regulated Products

Question 10 A patient says fluticasone HFA is used only when attacks occur and has stopped taking it as scheduled because no symptoms are present today. What correction is appropriate?

Answer choices

  1. A. Treat fluticasone as scheduled maintenance, not acute rescue; refer role confusion
  2. B. Confirm attack-only use because absence of symptoms makes maintenance therapy unnecessary
  3. C. Relabel fluticasone as immediate relief because all inhaled products have the same indication
  4. D. Remove the maintenance directions and retain only as-needed attack use

Correct answer

Treat fluticasone as scheduled maintenance, not acute rescue; refer role confusion

Objective/domain: 1. Medications

Source: Fluticasone Propionate HFA — Official Label

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